Clozaril works very slowly (like a snail) and it is affected by the amount of nicotine and or caffeine the person takes. (If that is even a factor) My son used both and we had to pick a level so to speak so he ended up with taking 150 mg twice a day and 1 large cup of coffee in the morning and no more than 10-12 cigarettes a day…with that it took about 8+ months and then one day he said “I don’t hear the voices anymore”
-Everyone is different in their response and speed of response but I applaud the ultimate effectiveness of this drug because without it my son would not be as well as he is today. He has been on it since 2009 or 2010 or thereabouts. It took a full year to see the full effects. Still year after year I see something else that’s better…maybe a perception or a way of thinking that seems improved.
Please if you take any advice from a mom with a son that has been on the drug for more than 10 years, be patient. It’s hard but please give it enough time at least a whole year. To help it along try to keep stress for your son extra low. And again if caffeine or nicotine is involved it has to be a stable amount every day. too much makes the clozapine less effective and little increases the strength in the body by a little bit. Somehow those chemicals are intertwined with how the clozapine works. They actually have a somewhat symbiotic relationship.
If those things are not a factor for your son then just make sure he takes the correct dosage every day and that his doctor has him on an effective therapeutic dose. My son was on 150 twice a day for many years and a couple of years ago the doctor tried reducing it to 125 mg twice a day to see if he could tolerate it and he did great so he stays on that now. Make sure to discuss all your findings with your son’s doctor and if that’s not possible write him or her a letter so they have a second perspective on your son’s progress. I am so happy to hear your son is compliant because that is half the battle…sounds like the pdoc may need to make some tweaks on the dosage. I wish you and your son the very best.