Seroquel taper causing withdrawal

Yes, @Terra, exactly the same thing here. My son was discharged from a hospital recently on 800 mg of Seroquel. We tried to taper, but when it got to 400 he started acting aggressive and/or delusional, I can’t remember which. He was put on 20 mg of olanzapine and 600 mg of Seroquel. The olanzapine has helped a good bit, I think. Still hears voices, but the aggressiveness is gone and I think the voices may be slowly getting better.

Were the palpitations heart rhythm problems, which is a known side-effect of quetiapine?

I’m hoping that my son can do olanzapine monotherapy.

If you look at https://family.schizophrenia.com/t/polypharmacy-vs-monotherapy/11131/4 you’ll see that risperidone + quetiapine is better than risperidone alone, so the psychiatrist may have known that, but of course the quetiapine had to be stopped because of the palpitations.