Motrin brand (or generic) ibuprofin and Alleve brand (or generic) naproxen are known to help somewhat (often tho not always) when anxiety repeatedly jams up the autonomic nervous system’s sympathetic branch into “fight or flight” and then “freak & fry” because actual inflammation in the brain’s limbic system appears to be linked to these “attacks.” Neither ibuprofin nor naproxen are tolerance- or dependence-inducing in standard (200mg) dosage.
Minor, benzodiazepine-class tranquilizers like Ativan lorazepam, Xanax alprazolam, Valium diazepam and Klonopin clonazepam are also pretty effective most of the time, BUT… they do induce tolerance and dependence, and they are The Most Popular substances there are for suicide attempts. (The stash must be hidden, and no sz patient should have a large stash for PRN use in his or her own possession.)
(Likewise, make sure there is no acetominophen around. An acetominophen OD is exceedingly dangerous because it chews up the liver in a hurry, and causes wretched suffering in the dying process.)
Moving past meds, "soothing attunement is increasingly considered the best interpersonal strategy and is widely used by psych techs and psych nurses in in-patient residential settings. Daniel Stern and Alan Schore are the big names in this technique, having developed it from observing D. W. Winnicott’s and Margaret Mahler’s “good enough mothers” with their temporarily agitated and emotionally overwhelmed small children. It requires a knowing and delicate hand, but it works so well when the attuner has one.
Moreover, pts can be taught by example to use it on themselves. One can Google all sorts of good stuff on this technique.