Family and Caregiver Schizophrenia Discussion Forum

Why it’s good to do your research before exploring alternatives

Good thing I noticed this on webmd:

Some medications are changed and broken down by the liver. Ginkgo might decrease how quickly the liver breaks down some medications. Taking ginkgo along with some medications that are changed by the liver might increase the effects and side effects of some medications. Before taking ginkgo talk to your healthcare provider if you take any medications that are changed by the liver. Some of these medications that are changed by the liver include clozapine (Clozaril), … haloperidol (Haldol)

The same thing with gingeng

Do your research!

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Hey windyhill
Had your daughter tried other medications before?
Supposibly newer generation antipsychotics cause less side effects
By the way there is a new antipsychotic coming out pretty soon which will have a lot less side effects than the ones currently out…

I forgot the name of it
I will look it up for you when I get time

Thank you for your post. My daughter right now is not taking any supplements at all. I want her to try the sarcosine, but she hasn’t as yet. She saw her psychiatrist this week and was confirmed as schizophrenic and was left on the haldol injection for now.

I wonder if ginkgo is taxing on the liver?
Of course, I mean when taken in combination with medication that definitely is a lot of work for a liver to process in the first place.

There are some individuals who have a higher metabolism and take up medication much faster than average, causing heavy side effects and reducing the duration of the intended effects.

Maybe ginkgo could be a good supplement for someone who has that genetic trait.

((For those who are wondering, you can confirm genetic traits such as metabolic rate of medication uptake (and a ton of other things) by combining a genetic test with a specialist who knows how to analyze the results for chemical and biological insight))

@oldladyblue
If you eventually can get your daughter to try sarcosine, you shouldn’t have any trouble… I did find that there are some foods that naturally have some sarcosine.

For those taking clozapine there is no additional benefit to taking sarcosine. Since your daughter is taking Haldol, this shouldn’t be an issue.

Sarcosine is readily present in a variety of food products, including: Egg yolks, legumes, nuts, certain vegetables, turkey, ham, and other meats

Administering sarcosine as an add-on treatment in patients with schizophrenia taking clozapine did not show any improvement in symptoms. This may be because clozapine may have increased the activity of NMDAR (N-methyl-D-aspartate receptor) to the maximum possible level, so the addition of sarcosine does not have any further beneficial effects [R].

No other drug interactions for sarcosine have been reported thus far.

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@TheSunshineMaras, I think I found it… so far it is being called ALKS-3831, made by Alkermes

https://www.fiercebiotech.com/biotech/alkermes-eyes-2019-filing-as-schizophrenia-drug-hits-mark-phase-3

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