Family and Caregiver Schizophrenia Discussion Forum

Clozaril sedation

Help ! My son started Clozaril about a month ago and is up to 200mg along with 7.5 haldol. He is sleeping 16 + hours a day. Does this get better ?

1 Like

Hi. My son did sleep for a lot of time after first starting too. Close to the same amount of time. Partly I think because the psychosis had worn him out, on top of the drug effect. He still sleeps 10-12 hours a day after 2+ years on clozaril, but my son is on 600mg per day all in one shot before bed. Your son’s body is trying to adjust to this med and it will take a bit. In my experience, this is all worth it.


Thank you for the response, very encouraging !

It definitely got better for my son on Clozaril, he was also sleeping 16+ hours a day in the beginning. It worried me so I asked his doctor about it and the doctor said that it was normal and it would improve in time. It did. If I remember right it took awhile maybe a few months I don’t recall but longer than a month for sure and was a gradual improvement. I can’t speak about the Haldol though because my son doesn’t take that one.


My son is starting the Clozaril today in the hospital. They say it’s once a week for 6 months to start. They say he was on so many meds and they weren’t working the way they wanted them to. It’ll be a whole different world if he sleeps so much. I wouldn’t know how to act… Is drooling a factor?

My son stared Clozaril about a month ago, and is up to 300 mg. which he takes between 7-8pm. He is sleeping about 12 hours a day, but I think the sleep is good for him right now, as he used to be up all hours of the night.

I think my son has more saliva at night, but I haven’t noticed any drooling during the day.

He is doing so much better than he was, and we are feeling hopeful.


Me too. Same situation so far. I like it personally for him. (My son is 26 yrs old) Hope it stays working.